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Cigarette Smoke Activates NFκB-Mediated Tnf-α Release from Mouse Middle Ear Cells

OBJECTIVES/HYPOTHESIS: Cigarette smoke exposure is a significant risk factor in the development of otitis media. NF-κB is a transcription factor known to mediate cigarette smoke effects in multiple cell types. We hypothesized that stimulation of murine middle ear epithelial cells (MEEC) with cigaret...

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Bibliographic Details
Main Authors: Preciado, Diego, Kuo, Elaine, Ashktorab, Samaneh, Manes, Peter, Rose, Mary
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107661/
https://ncbi.nlm.nih.gov/pubmed/21108432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.21014
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