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Coordinated DNA dynamics during the human telomerase catalytic cycle
The human telomerase reverse transcriptase (hTERT) utilizes a template within the integral RNA subunit (hTR) to direct extension of telomeres. Telomerase exhibits repeat addition processivity (RAP) and must therefore translocate the nascent DNA product into a new RNA:DNA hybrid register to prime eac...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107311/ https://ncbi.nlm.nih.gov/pubmed/24923681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5146 |
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