Improved small molecule drug release from in situ forming poly(lactic-co-glycolic acid) scaffolds incorporating poly(β-amino ester) and hydroxyapatite microparticles

In situ forming implants are an attractive choice for controlled drug release into a fixed location. Currently, rapidly solidifying solvent exchange systems suffer from a high initial burst, and sustained release behavior is tied to polymer precipitation and degradation rate. The present studies inv...

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Bibliographic Details
Main Authors: Fisher, Paul D., Palomino, Pablo, Milbrandt, Todd A., Hilt, J. Zach, Puleo, David A.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106901/
https://ncbi.nlm.nih.gov/pubmed/24903524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09205063.2014.923368
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