Reelin Induces Erk1/2 Signaling in Cortical Neurons Through a Non-canonical Pathway

Reelin is an extracellular protein that controls many aspects of pre- and postnatal brain development and function. The molecular mechanisms that mediate postnatal activities of Reelin are not well understood. Here, we first set out to express and purify the full length Reelin protein and a biologic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Gum Hwa, Chhangawala, Zinal, von Daake, Sventja, Savas, Jeffrey N., Yates, John R., Comoletti, Davide, D'Arcangelo, Gabriella
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106344/
https://ncbi.nlm.nih.gov/pubmed/24876378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.576249
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