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Aspergillus oryzae CsyB Catalyzes the Condensation of Two β-Ketoacyl-CoAs to Form 3-Acetyl-4-hydroxy-6-alkyl-α-pyrone

The type III polyketide synthases from fungi produce a variety of secondary metabolites including pyrones, resorcinols, and resorcylic acids. We previously reported that CsyB from Aspergillus oryzae forms α-pyrone csypyrone B compounds when expressed in A. oryzae. Feeding experiments of labeled acet...

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Detalhes bibliográficos
Main Authors: Hashimoto, Makoto, Koen, Tsukasa, Takahashi, Hiroaki, Suda, Chihiro, Kitamoto, Katsuhiko, Fujii, Isao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106316/
https://ncbi.nlm.nih.gov/pubmed/24895122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.569095
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