Mutant rat phosphatidylinositol/phosphatidylcholine transfer proteins specifically defective in phosphatidylinositol transfer: implications for the regulation of phospholipid transfer activity.

The mammalian phosphatidylinositol/phosphatidylcholine transfer proteins (PI-TPs) catalyze exchange of phosphatidylinositol (PI) or phosphatidylcholine (PC) between membrane bilayers in vitro. We find that Ser-25, Thr-59, Pro-78, and Glu-248 make up a set of rat (r) PI-TP residues, substitution of w...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Alb, J G, Gedvilaite, A, Cartee, R T, Skinner, H B, Bankaitis, V A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41060/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.19.8826
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