Varenicline decreases ethanol intake and increases dopamine release via neuronal nicotinic acetylcholine receptors in the nucleus accumbens

BACKGROUND AND PURPOSE: Varenicline, a neuronal nicotinic acetylcholine receptor (nAChR) modulator, decreases ethanol consumption in rodents and humans. The proposed mechanism of action for varenicline to reduce ethanol consumption has been through modulation of dopamine (DA) release in the nucleus...

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Detalhes bibliográficos
Main Authors: Feduccia, A A, Simms, J A, Mill, D, Yi, H Y, Bartlett, S E
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105930/
https://ncbi.nlm.nih.gov/pubmed/24628360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12690
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