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Analyzing networks of phenotypes in complex diseases: methodology and applications in COPD

BACKGROUND: The investigation of complex disease heterogeneity has been challenging. Here, we introduce a network-based approach, using partial correlations, that analyzes the relationships among multiple disease-related phenotypes. RESULTS: We applied this method to two large, well-characterized st...

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Bibliografske podrobnosti
Main Authors: Chu, Jen-hwa, Hersh, Craig P, Castaldi, Peter J, Cho, Michael H, Raby, Benjamin A, Laird, Nan, Bowler, Russell, Rennard, Stephen, Loscalzo, Joseph, Quackenbush, John, Silverman, Edwin K
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105829/
https://ncbi.nlm.nih.gov/pubmed/24964944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-78
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