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Brain-specific knockdown of miR-29 results in neuronal cell death and ataxia in mice

Several microRNAs have been implicated in neurogenesis, neuronal differentiation, neurodevelopment, and memory. Development of miRNA-based therapeutics, however, needs tools for effective miRNA modulation, tissue-specific delivery, and in vivo evidence of functional effects following the knockdown o...

詳細記述

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書誌詳細
主要な著者: Roshan, Reema, Shridhar, Shruti, Sarangdhar, Mayuresh A., Banik, Arpita, Chawla, Mrinal, Garg, Manali, Singh, Vijay PAL, Pillai, Beena
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105753/
https://ncbi.nlm.nih.gov/pubmed/24958907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.044008.113
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