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Activated Platelets from Diabetic Rats Cause Endothelial Dysfunction by Decreasing Akt/Endothelial NO Synthase Signaling Pathway

Diabetes is associated with endothelial dysfunction and platelet activation, both of which may contribute to increased cardiovascular risk. The purpose of this study was to characterize circulating platelets in diabetes and clarify their effects on endothelial function. Male Wistar rats were injecte...

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Detalhes bibliográficos
Main Authors: Ishida, Keiko, Taguchi, Kumiko, Matsumoto, Takayuki, Kobayashi, Tsuneo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105471/
https://ncbi.nlm.nih.gov/pubmed/25047034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102310
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