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Hs3st3-modified heparan sulfate controls KIT+ progenitor expansion by regulating 3-O-sulfotransferases

The exquisite control of growth factor function by heparan sulfate (HS) is dictated by the tremendous structural heterogeneity of sulfated modifications. It is not known how specific HS structures control growth factor-dependent progenitor expansion during organogenesis. We isolated KIT+ progenitors...

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Detalhes bibliográficos
Main Authors: Patel, Vaishali N., Lombaert, Isabelle M. A., Cowherd, Samuel N., Shworak, Nicholas W., Xu, Yongmei, Liu, Jian, Hoffman, Matthew P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105206/
https://ncbi.nlm.nih.gov/pubmed/24960693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.04.024
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