SPE-8, a protein-tyrosine kinase, localizes to the spermatid cell membrane through interaction with other members of the SPE-8 group spermatid activation signaling pathway in C. elegans

BACKGROUND: The SPE-8 group gene products transduce the signal for spermatid activation initiated by extracellular zinc in C. elegans. Mutations in the spe-8 group genes result in hermaphrodite-derived spermatids that cannot activate to crawling spermatozoa, although spermatids from mutant males act...

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Bibliographic Details
Main Authors: Muhlrad, Paul J, Clark, Jessica N, Nasri, Ubaydah, Sullivan, Nicholas G, LaMunyon, Craig W
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105102/
https://ncbi.nlm.nih.gov/pubmed/25022984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-15-83
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