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Exercise improves cognition and hippocampal plasticity in APOE ε4 mice

BACKGROUND: Human studies on exercise, cognition, and apolipoprotein E (APOE) genotype show that ε4 carriers may benefit from regular physical activity. METHODS: We examined voluntary wheel-running, memory, and hippocampal plasticity in APOE ε3 and APOE ε4 transgenic mice at 10–12 months of age. RES...

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Detalhes bibliográficos
Main Authors: Nichol, Kathryn, Deeny, Sean P., Seif, Joseph, Camaclang, Kevin, Cotman, Carl W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105011/
https://ncbi.nlm.nih.gov/pubmed/19560099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2009.02.006
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