Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes

We developed modified RBCs to serve as carriers for systemic delivery of a wide array of payloads. These RBCs contain modified proteins on their plasma membrane, which can be labeled in a sortase-catalyzed reaction under native conditions without inflicting damage to the target membrane or cell. Sor...

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Detalhes bibliográficos
Principais autores: Shi, Jiahai, Kundrat, Lenka, Pishesha, Novalia, Bilate, Angelina, Theile, Chris, Maruyama, Takeshi, Dougan, Stephanie K., Ploegh, Hidde L., Lodish, Harvey F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104923/
https://ncbi.nlm.nih.gov/pubmed/24982154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409861111
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