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IL-33/ST2 axis promotes mast cell survival via BCLXL

Mast cells (MC) are potent innate immune cells that accumulate in chronically inflamed tissues. MC express the IL-33 receptor IL-1 receptor-related protein ST2 at high level, and this IL-1 family cytokine both activates MC directly and primes them to respond to other proinflammatory signals. Whether...

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Detalhes bibliográficos
Main Authors: Wang, Jun-Xia, Kaieda, Shinjiro, Ameri, Sarah, Fishgal, Nadia, Dwyer, Daniel, Dellinger, Anthony, Kepley, Christopher L., Gurish, Michael F., Nigrovic, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104908/
https://ncbi.nlm.nih.gov/pubmed/24982172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404182111
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