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Cep164 triggers ciliogenesis by recruiting Tau tubulin kinase 2 to the mother centriole

Primary cilia play critical roles in development and disease. Their assembly is triggered by mature centrioles (basal bodies) and requires centrosomal protein 164kDa (Cep164), a component of distal appendages. Here we show that loss of Cep164 leads to early defects in ciliogenesis, reminiscent of th...

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Detalhes bibliográficos
Main Authors: Čajánek, Lukáš, Nigg, Erich A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104846/
https://ncbi.nlm.nih.gov/pubmed/24982133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401777111
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