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A “push and slide” mechanism allows sequence-insensitive translocation of secretory proteins by the SecA ATPase
In bacteria, most secretory proteins are translocated across the plasma membrane by the interplay of the SecA ATPase and the SecY channel. How SecA moves a broad range of polypeptide substrates is only poorly understood. Here, we show that SecA moves polypeptides through the SecY channel by a “push...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104599/ https://ncbi.nlm.nih.gov/pubmed/24906156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.063 |
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