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Disease-modifying genes and monogenic disorders: experience in cystic fibrosis
The mechanisms responsible for the determination of phenotypes are still not well understood; however, it has become apparent that modifier genes must play a considerable role in the phenotypic heterogeneity of Mendelian disorders. Significant advances in genetic technologies and molecular medicine...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104546/ https://ncbi.nlm.nih.gov/pubmed/25053892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S18675 |
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