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TRPV1 antagonist capsazepine suppresses 4-AP-induced epileptiform activity in vitro and electrographic seizures in vivo

Transient receptor potential vanilloid 1 (TRPV1) is a cation-permeable ion channel found in the peripheral and central nervous systems. The membrane surface expression of TRPV1 is known to occur in neuronal cell bodies and sensory neuron axons. TRPV1 receptors are also expressed in the hippocampus,...

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Autori principali: Gonzalez-Reyes, Luis E., Ladas, Thomas P., Chiang, Chia-Chu, Durand, Dominique M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104534/
https://ncbi.nlm.nih.gov/pubmed/24145133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.10.010
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