H(2)S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO–TRPA1–CGRP signalling pathway

Nitroxyl (HNO) is a redox sibling of nitric oxide (NO) that targets distinct signalling pathways with pharmacological endpoints of high significance in the treatment of heart failure. Beneficial HNO effects depend, in part, on its ability to release calcitonin gene-related peptide (CGRP) through an...

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Detalhes bibliográficos
Main Authors: Eberhardt, Mirjam, Dux, Maria, Namer, Barbara, Miljkovic, Jan, Cordasic, Nada, Will, Christine, Kichko, Tatjana I., de la Roche, Jeanne, Fischer, Michael, Suárez, Sebastián A., Bikiel, Damian, Dorsch, Karola, Leffler, Andreas, Babes, Alexandru, Lampert, Angelika, Lennerz, Jochen K., Jacobi, Johannes, Martí, Marcelo A., Doctorovich, Fabio, Högestätt, Edward D., Zygmunt, Peter M., Ivanovic-Burmazovic, Ivana, Messlinger, Karl, Reeh, Peter, Filipovic, Milos R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104458/
https://ncbi.nlm.nih.gov/pubmed/25023795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5381
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