Redox Properties of Human Hemoglobin in Complex with Fractionated Dimeric and Polymeric Human Haptoglobin

Haptoglobin (Hp) is an abundant and conserved plasma glycoprotein, which binds acellular adult hemoglobin (Hb) dimers with high affinity and facilitates their rapid clearance from circulation following hemolysis. Humans possess three main phenotypes of Hp, designated Hp 1-1, Hp 2-1, and Hp 2-2. Thes...

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Autors principals: Mollan, Todd L., Jia, Yiping, Banerjee, Sambuddha, Wu, Gang, Kreulen, R. Timothy, Tsai, Ah-Lim, Olson, John S., Crumbliss, Alvin L., Alayash, Abdu I.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104362/
https://ncbi.nlm.nih.gov/pubmed/24486321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.01.030
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