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A Molecular Profile of Cocaine Abuse Includes the Differential Expression of Genes that Regulate Transcription, Chromatin, and Dopamine Cell Phenotype

Chronic drug abuse, craving, and relapse are thought to be linked to long-lasting changes in neural gene expression arising through transcriptional and chromatin-related mechanisms. The key contributions of midbrain dopamine (DA)-synthesizing neurons throughout the addiction process provide a compel...

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Detalhes bibliográficos
Main Authors: Bannon, Michael J, Johnson, Magen M, Michelhaugh, Sharon K, Hartley, Zachary J, Halter, Steven D, David, James A, Kapatos, Gregory, Schmidt, Carl J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104338/
https://ncbi.nlm.nih.gov/pubmed/24642598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.70
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