Autistic-Like Syndrome in Mu Opioid Receptor Null Mice is Relieved by Facilitated mGluR4 Activity

The etiology of Autism Spectrum Disorders (ASDs) remains largely unknown. Identifying vulnerability genes for autism represents a major challenge in the field and allows the development of animal models for translational research. Mice lacking the mu opioid receptor gene (Oprm1(−/−)) were recently p...

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Autors principals: Becker, Jérôme AJ, Clesse, Daniel, Spiegelhalter, Coralie, Schwab, Yannick, Le Merrer, Julie, Kieffer, Brigitte L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104328/
https://ncbi.nlm.nih.gov/pubmed/24619243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.59
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