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EQUILIBRIUM AND DYNAMIC DESIGN PRINCIPLES FOR BINDING MOLECULES ENGINEERED FOR REAGENTLESS BIOSENSORS
Reagentless biosensors rely on the interaction of a binding partner and its target to generate a change in fluorescent signal using an environment sensitive fluorophore or Förster Resonance Energy Transfer. Binding affinity can exert a significant influence on both the equilibrium and the dynamic re...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104283/ https://ncbi.nlm.nih.gov/pubmed/24814226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2014.04.036 |
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