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Utilizing Cell-matrix Interactions to Modulate Gene Transfer to Stem Cells Inside Hyaluronic Acid Hydrogels

The effective delivery of DNA locally would increase the applicability of gene therapy in tissue regeneration, where diseased tissue is to be repaired in situ. One promising approach is to use hydrogel scaffolds to encapsulate and deliver plasmid DNA in the form of nanoparticles to the diseased tiss...

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Bibliographic Details
Main Authors: Gojgini, Shiva, Tokatlian, Talar, Segura, Tatiana
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104282/
https://ncbi.nlm.nih.gov/pubmed/21823632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200171d
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