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Cytochrome P450 Gene Variants, Race, and Mortality Among Clopidogrel Treated Patients Following Acute Myocardial Infarction

BACKGROUND: Clopidogrel is recommended after acute myocardial infarction (AMI) but has variable efficacy and safety, in part related to the effect of cytochrome P450 (CYP) polymorphisms on its metabolism. The effect of CYP polymorphisms on cardiovascular events among clopidogrel-treated patients aft...

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Detalhes bibliográficos
Main Authors: Cresci, Sharon, Depta, Jeremiah P., Lenzini, Petra A., Li, Allie Y., Lanfear, David E., Province, Michael A., Spertus, John A., Bach, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104276/
https://ncbi.nlm.nih.gov/pubmed/24762860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.113.000303
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