Selective Chemical Modulation of Gene Transcription Favors Oligodendrocyte Lineage Progression

Lysine acetylation regulates gene expression through modulating protein-protein interactions in chromatin. Chemical inhibition of acetyl-lysine binding bromodomains of the major chromatin regulators BET (bromodomain and extra-terminal domain) proteins, has been shown to effectively block cell prolif...

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Detalhes bibliográficos
Main Authors: Gacias, Mar, Gerona-Navarro, Guillermo, Plotnikov, Alexander N., Zhang, Guangtao, Zeng, Lei, Kaur, Jasbir, Moy, Gregory, Rusinova, Elena, Rodriguez, Yoel, Matikainen, Bridget, Vincek, Adam, Joshua, Jennifer, Casaccia, Patrizia, Zhou, Ming-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104156/
https://ncbi.nlm.nih.gov/pubmed/24954007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.05.009
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