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Contributions of Cell Growth and Biochemical Reactions to Nongenetic Variability of Cells

Cell-to-cell variability in the molecular composition of isogenic, steady-state growing cells arises spontaneously from the inherent stochasticity of intracellular biochemical reactions and cell growth. Here, we present a general decomposition of the total variance in the copy number per cell of a p...

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Detalhes bibliográficos
Main Authors: Schwabe, Anne, Bruggeman, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104058/
https://ncbi.nlm.nih.gov/pubmed/25028872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.05.004
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