Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction.

The interleukin 2 receptor (IL-2R) consists of three subunits, the IL-2R alpha, IL-2R beta c, and IL-2R gamma c chains. Two Janus family protein tyrosine kinases (PTKs), Jak1 and Jak3, were shown to associate with IL-2R beta c and IL-2R gamma c, respectively, and their PTK activities are increased a...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kawahara, A, Minami, Y, Miyazaki, T, Ihle, J N, Taniguchi, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41039/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568005/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.19.8724
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