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Karyometry: Correction algorithm for differences in staining

OBJECTIVES: An algorithm is described which allows the correction of differences in staining of histopathologic sections while preserving chromatin texture. METHODS: In order to preserve the texture of the nuclear chromatin in the corrected digital imagery, it is necessary to correct the images pixe...

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Autores principales: Bartels, Peter H., Bartels, Hubert G., Alberts, David S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103874/
https://ncbi.nlm.nih.gov/pubmed/19402382
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