BDNF Is Associated with SFRP1 Expression in Luminal and Basal-Like Breast Cancer Cell Lines and Primary Breast Cancer Tissues: A Novel Role in Tumor Suppression?

Secreted frizzled related protein 1 (SFRP1) functions as an important inhibitor of the Wnt pathway and is a known tumor suppressor gene, which is epigenetically silenced in a variety of tumors e.g. in breast cancer. However, it is still unclear how SFRP1 exactly affects the Wnt pathway. Our aim was...

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Hlavní autoři: Huth, Laura, Rose, Michael, Kloubert, Veronika, Winkens, Wiebke, Schlensog, Martin, Hartmann, Arndt, Knüchel, Ruth, Dahl, Edgar
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103839/
https://ncbi.nlm.nih.gov/pubmed/25036590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102558
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