Oxidative Stress Induced Age Dependent Meibomian Gland Dysfunction in Cu, Zn-Superoxide Dismutase-1 (Sod1) Knockout Mice

PURPOSE: The purpose of our study was to investigate alterations in the meibomian gland (MG) in Cu, Zn-Superoxide Dismutase-1 knockout (Sod1 (−/−)) mouse. METHODS: Tear function tests [Break up time (BUT) and cotton thread] and ocular vital staining test were performed on Sod1 (−/−) male mice (n = 2...

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Main Authors: Ibrahim, Osama M. A., Dogru, Murat, Matsumoto, Yukihiro, Igarashi, Ayako, Kojima, Takashi, Wakamatsu, Tais Hitomi, Inaba, Takaaki, Shimizu, Takahiko, Shimazaki, Jun, Tsubota, Kazuo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103776/
https://ncbi.nlm.nih.gov/pubmed/25036096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099328
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