Vehicular Emissions Induce Vascular MMP-9 Expression and Activity Associated with Endothelin-1 Mediated Pathways

OBJECTIVE: Mechanisms of air pollution-induced exacerbation of cardiovascular disease are currently unknown, thus we examined the roles of vascular endothelin-1 (ET-1) and reactive oxygen species (ROS) in regulating mediators of vascular remodeling, namely matrix metalloproteinases (MMPs), following...

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Detalhes bibliográficos
Main Authors: Lund, Amie K., Lucero, JoAnn, Lucas, Selitá, Madden, Michael C., McDonald, Jacob D., Seagrave, Jean-Clare, Knuckles, Travis L., Campen, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103743/
https://ncbi.nlm.nih.gov/pubmed/19150882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.176107
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