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Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer’s disease

Alzheimer’s disease (AD), characterized by cognitive decline, has emerged as a disease of synaptic failure. The present study reveals an unanticipated role of erythropoietin-producing hepatocellular A4 (EphA4) in mediating hippocampal synaptic dysfunctions in AD and demonstrates that blockade of the...

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מידע ביבליוגרפי
Main Authors: Fu, Amy K. Y., Hung, Kwok-Wang, Huang, Huiqian, Gu, Shuo, Shen, Yang, Cheng, Elaine Y. L., Ip, Fanny C. F., Huang, Xuhui, Fu, Wing-Yu, Ip, Nancy Y.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103318/
https://ncbi.nlm.nih.gov/pubmed/24958880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405803111
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