HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels

High-mobility group A1 (HMGA1) proteins are architectural chromatinic proteins, abundantly expressed during embryogenesis and in most cancer tissues, but expressed at low levels or absent in normal adult tissues. Several studies have demonstrated that HMGA1 proteins play a causal role in neoplastic...

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Detalhes bibliográficos
Main Authors: Puca, Francesca, Colamaio, Marianna, Federico, Antonella, Gemei, Marica, Tosti, Nadia, Bastos, André Uchimura, Vecchio, Luigi Del, Pece, Salvatore, Battista, Sabrina, Fusco, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102806/
https://ncbi.nlm.nih.gov/pubmed/24833610
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