Tumor cell apoptosis mediated by cytoplasmic ING1 is associated with improved survival in oral squamous cell carcinoma patients

The ING1 epigenetic regulator and tumor suppressor plays a central role in apoptosis. The Ing1 gene is functionally inactivated in many cancer types but is rarely mutated. Although most studies have implicated the major ING1 isoform, p33ING1b, in nuclear apoptotic signalling, we recently discovered...

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Detalhes bibliográficos
Main Authors: Bose, Pinaki, Thakur, Satbir S., Brockton, Nigel T., Klimowicz, Alexander C., Kornaga, Elizabeth, Nakoneshny, Steven C., Riabowol, Karl T., Dort, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102804/
https://ncbi.nlm.nih.gov/pubmed/24912621
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