Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production

Chromosomal band 11q13 seems to be one of the most frequently amplified lesions in human cancer, including esophageal squamous cell cancer (ESCC). The oral cancer overexpressed 1 (ORAOV1) gene has been identified within this region, but its detailed biological function in human ESCC remains largely...

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Detalhes bibliográficos
Main Authors: Togashi, Yosuke, Arao, Tokuzo, Kato, Hiroaki, Matsumoto, Kazuko, Terashima, Masato, Hayashi, Hidetoshi, de Velasco, Marco A, Fujita, Yoshihiko, Kimura, Hideharu, Yasuda, Takushi, Shiozaki, Hitoshi, Nishio, Kazuto
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102783/
https://ncbi.nlm.nih.gov/pubmed/24930674
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