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A cell cycle-regulated Slx4–Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication
A key function of the cellular DNA damage response is to facilitate the bypass of replication fork-stalling DNA lesions. Template switch reactions allow such a bypass and involve the formation of DNA joint molecules (JMs) between sister chromatids. These JMs need to be resolved before cell division;...
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Huvudupphovsmän: | , , , , , , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
Cold Spring Harbor Laboratory Press
2014
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4102767/ https://ncbi.nlm.nih.gov/pubmed/25030699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.240515.114 |
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