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1α,25(OH)(2)-Dihydroxyvitamin D(3)/VDR protects the skin from UVB-induced tumor formation by interacting with the β-catenin pathway
Ultra violet (UV) irradiation, in particular UVB, is the single most important carcinogen for skin tumor formation. UVB induces genetic mutations and immune suppression, which lead to abnormal cell proliferation and eventually tumor formation. Previously studies from our group and others demonstrate...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4102608/ https://ncbi.nlm.nih.gov/pubmed/23026511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2012.09.024 |
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