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Dietary Methanol Regulates Human Gene Activity

Methanol (MeOH) is considered to be a poison in humans because of the alcohol dehydrogenase (ADH)-mediated conversion of MeOH to formaldehyde (FA), which is toxic. Our recent genome-wide analysis of the mouse brain demonstrated that an increase in endogenous MeOH after ADH inhibition led to a signif...

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Autori principali: Shindyapina, Anastasia V., Petrunia, Igor V., Komarova, Tatiana V., Sheshukova, Ekaterina V., Kosorukov, Vyacheslav S., Kiryanov, Gleb I., Dorokhov, Yuri L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102594/
https://ncbi.nlm.nih.gov/pubmed/25033451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102837
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