Oxygen Transport and Stem Cell Aggregation in Stirred-Suspension Bioreactor Cultures

Stirred-suspension bioreactors are a promising modality for large-scale culture of 3D aggregates of pluripotent stem cells and their progeny. Yet, cells within these clusters experience limitations in the transfer of factors and particularly O(2) which is characterized by low solubility in aqueous m...

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Bibliographic Details
Main Authors: Wu, Jincheng, Rostami, Mahboubeh Rahmati, Cadavid Olaya, Diana P., Tzanakakis, Emmanuel S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102498/
https://ncbi.nlm.nih.gov/pubmed/25032842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102486
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