Recombinant Antigens Expressed in Pichia pastoris for the Diagnosis of Sleeping Sickness Caused by Trypanosoma brucei gambiense

BACKGROUND: Screening tests for gambiense sleeping sickness, such as the CATT/T. b. gambiense and a recently developed lateral flow tests, are hitherto based on native variant surface glycoproteins (VSGs), namely LiTat 1.3 and LiTat 1.5, purified from highly virulent trypanosome strains grown in rod...

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Bibliographic Details
Main Authors: Rogé, Stijn, Van Nieuwenhove, Liesbeth, Meul, Magali, Heykers, Annick, Brouwer de Koning, Annette, Bebronne, Nicolas, Guisez, Yves, Büscher, Philippe
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102443/
https://ncbi.nlm.nih.gov/pubmed/25032684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003006
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