Leishmania amazonensis Amastigotes Highly Express a Tryparedoxin Peroxidase Isoform That Increases Parasite Resistance to Macrophage Antimicrobial Defenses and Fosters Parasite Virulence

Professional phagocytes generate a myriad of antimicrobial molecules to kill invading microorganisms, of which nitrogen oxides are integral in controlling the obligate intracellular pathogen Leishmania. Although reactive nitrogen species produced by the inducible nitric oxide synthase (iNOS) can pro...

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Bibliografske podrobnosti
Main Authors: Henard, Calvin A., Carlsen, Eric D., Hay, Christie, Kima, Peter E., Soong, Lynn
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102420/
https://ncbi.nlm.nih.gov/pubmed/25033301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003000
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