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Intact NKG2D-Independent Function of NK Cells Chronically Stimulated with the NKG2D Ligand Rae-1

Human tumors frequently express membrane-bound or soluble NK group 2, member D (NKG2D) ligands. This results in chronic engagement of NKG2D on the surfaces of NK and CD8(+) T cells and rapid internalization of the receptor. Although it is well appreciated that this phenomenon impairs NKG2D-dependent...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Champsaur, Marine, Beilke, Joshua N., Ogasawara, Kouetsu, Koszinowski, Ulrich H., Jonjic, Stipan, Lanier, Lewis L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102003/
https://ncbi.nlm.nih.gov/pubmed/20530257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000397
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