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High Glucose Aggravates the Detrimental Effects of Pancreatic Stellate Cells on Beta-Cell Function

Background and Aims. We here assess the effects of PSCs on β-cell function and apoptosis in vivo and in vitro. Materials and Methods. PSCs were transplanted into Wistar and Goto-Kakizaki (GK) rats. Sixteen weeks after transplantation, β-cell function, apoptosis, and islet fibrosis were assessed. In...

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Detalhes bibliográficos
Main Authors: Zha, Min, Xu, Wei, Zhai, Qing, Li, Fengfei, Chen, Bijun, Sun, Zilin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101948/
https://ncbi.nlm.nih.gov/pubmed/25097548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/165612
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