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Autophagy in pulmonary macrophages mediates lung inflammatory injury via NLRP3 inflammasome activation during mechanical ventilation

The inflammatory response is a primary mechanism in the pathogenesis of ventilator-induced lung injury. Autophagy is an essential, homeostatic process by which cells break down their own components. We explored the role of autophagy in the mechanisms of mechanical ventilation-induced lung inflammato...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Yang, Liu, Gongjian, Dull, Randal O., Schwartz, David E., Hu, Guochang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101793/
https://ncbi.nlm.nih.gov/pubmed/24838752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00083.2014
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