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Weighted Interaction SNP Hub (WISH) network method for building genetic networks for complex diseases and traits using whole genome genotype data

BACKGROUND: High-throughput genotype (HTG) data has been used primarily in genome-wide association (GWA) studies; however, GWA results explain only a limited part of the complete genetic variation of traits. In systems genetics, network approaches have been shown to be able to identify pathways and...

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Detalhes bibliográficos
Main Authors: Kogelman, Lisette JA, Kadarmideen, Haja N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101698/
https://ncbi.nlm.nih.gov/pubmed/25032480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-S2-S5
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