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Rim formation is not a prerequisite for distribution of cone photoreceptor outer segment proteins

Retinal degeneration slow (RDS/PRPH2) is critical for the formation of the disc/lamella rim in photoreceptor outer segments (OSs), but plays a different role in rods vs. cones. Without RDS, rods fail to form OSs, however, cones lacking RDS (in the rds(−/−)/Nrl(−/−)) exhibit balloon-like OSs devoid o...

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Hlavní autoři: Conley, Shannon M., Al-Ubaidi, Muayyad R., Han, Zongchao, Naash, Muna I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101662/
https://ncbi.nlm.nih.gov/pubmed/24736412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-251397
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