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Opiorphin is a master regulator of the hypoxic response in corporal smooth muscle cells
Men with sickle cell disease (SCD) risk developing priapism. Recognizing that SCD is a disease of hypoxia, we investigated the effect of hypoxia on gene expression in corporal smooth muscle (CSM) cells. Rat CSM cells in vitro were treated with CoCl(2) or low oxygen tension to mimic hypoxia. Hypoxic...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Federation of American Societies for Experimental Biology
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4101653/ https://ncbi.nlm.nih.gov/pubmed/24803544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-248708 |
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