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Opiorphin is a master regulator of the hypoxic response in corporal smooth muscle cells

Men with sickle cell disease (SCD) risk developing priapism. Recognizing that SCD is a disease of hypoxia, we investigated the effect of hypoxia on gene expression in corporal smooth muscle (CSM) cells. Rat CSM cells in vitro were treated with CoCl(2) or low oxygen tension to mimic hypoxia. Hypoxic...

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Detalhes bibliográficos
Main Authors: Fu, Shibo, Tar, Moses Tarndie, Melman, Arnold, Davies, Kelvin Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101653/
https://ncbi.nlm.nih.gov/pubmed/24803544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-248708
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